CJC1295 No DAC is a growth hormone releasing hormone (GHRH) analog and is designed to stimulate the release of growth hormone from the pituitary gland. Research studies have shown that CJC-1295 No DAC has several potential benefits, including increased muscle growth, fat loss, improved bone density, and enhanced immune system function. Studies indicate it may also have neuroprotective properties and promote improved sleep patterns.
CJC-1295 no DAC, also known as Modified GRF 1-29 peptide or tetrasubstituted GRF 1-29, is a synthetic peptide with 29 amino acids that functions as a growth hormone-releasing hormone (GHRH) analogue.It is designed to stimulate the secretion of growth hormone (GH) from the pituitary gland, promoting several physiological effects, including enhanced protein synthesis, increased insulin release from the pancreas, and improved bowel motility and gastric function. This process contributes to better body composition and elevated overall energy levels.
Unlike its counterpart, CJC-1295 with drug affinity complex (DAC), CJC-1295 without DAC has a shorter half-life, resulting in a more immediate yet transient effect on GH secretion. This peptide is often researched for its potential therapeutic applications in conditions related to growth hormone deficiency and for facilitating muscle growth in healthy adults.
Use and administration of CJC-1295 no DAC should be conducted under professional guidance due to possible side effects, including nausea and other reactions.
CJC-1295 without DAC, or mod GRF, operates by mimicking the body’s natural growth hormone-releasing hormone (GHRH), binding to specific GHRH receptors located on the pituitary gland. This interaction triggers a cascade of intracellular events that culminate in the enhanced secretion of growth hormone (GH) into the bloodstream.
The increase in GH levels promotes several anabolic processes, such as heightened protein synthesis and improved muscle mass. The mechanism also involves the modulation of various endocrine pathways, affecting insulin-like growth factor 1 (IGF-1) production, which further contributes to its physiological effects.
Due to its rapid action and shorter half-life, CJC-1295 no DAC is often administrated in a manner that allows for more frequent dosing to maintain elevated GH levels, thereby maximising its potential benefits for researchers.
PubChem CID: 91976842
Molecular Formula: C152H252N44O42
Molecular Weight: 3367.9 g/mol
Sequence:
H-DL-Tyr-DL-Ala-DL-Asp-DL-Ala-DL-xiIle-DL-Phe-DL-xiThr-DL-Gln-DL-Ser-DL-Tyr-DL-Arg-DL-Lys-DL-Val-DL-Leu-DL-Ala-DL-Gln-DL-Leu-DL-Ser-DL-Ala-DL-Arg-DL-Lys-DL-Leu-DL-Leu-DL-Gln-DL-Asp-DL-xiIle-DL-Leu-DL-Ser-DL-Arg-NH2
View our CJC-1295 no DAC High-Performance Liquid Chromatography (HPLC) Certificate here.
Source: PubChem
Buy CJC-1295 no DAC and Ipamorelin Blend Nasal Spray
Buy CJC-1295 no DAC and Ipamorelin Blend Nasal Spray for clinical research from Norway Direct Sarms, available in 15ml and 30ml bottles.
This blend is also offered in a 2.5mg vial and a pre-mixed 2mg pen.
You can also buy CJC-1295 No DAC and GHRP-6 Blend for research purposes to investigate their combined effects on growth hormone modulation and metabolic processes. This blend is available in a 2.5mg vial and 15ml and 30ml nasal sprays.
Additionally Direct Sarms Norway also offers cjc-1295 no dac and hgh fragment 176-191 blend for sale. Buy CJC-1295 No DAC and HGH Fragment 176-191 Blend, a targeted peptide combination designed to enhance growth hormone release while promoting fat loss and metabolic health in research environments.
Potential Benefits of Ipamorelin and CJC-1295 No DAC Blend:
Potential benefits of CJC-1295 no DAC and GHRP-2 Peptide Stack:
Buy CJC-1295 no DAC and GHRP-2 Peptide Stack
Buy CJC-1295 no DAC and GHRP-2 Peptide Stack for research from Direct Sarms Norway.
Direct SARMs Norway also offers a stack with Hexarelin, a notable growth hormone secretagogue. You can buy CJC-1295 no DAC and Hexarelin peptide stack here. Hexarelin is a growth hormone secretagogue that activates the ghrelin receptor, boosting GH release and supporting cellular health and recovery. This combination enhances muscle growth, fat metabolism, and recovery times, making it a valuable choice for researchers exploring growth hormone dynamics and its health and performance applications.
Where can I buy CJC-1295 no DAC peptide?
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What is the half life of CJC-1295 without DAC?
The half-life of CJC-1295 no DAC is approximately 30 minutes to 1 hour when administered subcutaneously. This relatively short half-life is due to the absence of a drug affinity complex (DAC), which typically extends the duration of action for similar peptides. However, despite its brief half-life, CJC-1295 no DAC promotes sustained growth hormone release due to its action of mimicking growth hormone-releasing hormone (GHRH), allowing for prolonged effects on growth hormone levels in the bloodstream. Researchers should be mindful of this when planning the dosing schedule to maximise the peptide’s benefits.
What is the difference between CJC-1295 DAC and CJC-1295 no DAC?
CJC-1295 DAC (Drug Affinity Complex) and CJC-1295 No DAC are synthetic peptides that stimulate growth hormone release, but they differ in structure and pharmacokinetics. CJC-1295 DAC has a modification that extends its half-life, allowing for less frequent dosing and a sustained release of growth hormone, which is convenient for researchers who prefer administering fewer injections.
In contrast, CJC-1295 No DAC has a shorter half-life, leading to quicker clearance from the body and requiring more frequent administration to maintain elevated growth hormone levels. Both peptides aim to boost growth hormone secretion, but the choice between them may depend on individual preferences for dosing frequency and desired duration of effect.
What is the legal status of CJC-1295 no DAC?
The legal status of CJC-1295 no DAC varies worldwide. In the US, it is not FDA-approved for medical use but permitted for research. Similarly, in the UK and Europe, it’s available for research but not human use. In Australia, the TGA has classified it as an unregistered substance, making therapeutic use illegal without approval. Individuals should consult local laws and seek professional advice for compliance.
What are the benefits of CJC-1295 no DAC?
The benefits include increased muscle mass, improved fat loss, enhanced recovery and tissue regeneration, better sleep quality, increased energy levels, and potential improvements in cognitive function and immune response.
What are the side effects of CJC-1295 no DAC?
Potential side effects may include injection site reactions, water retention, and changes in mood. Long-term effects are still being studied, and researchers should closely monitor the health of their test subjects.
For more information, explore our latest blog posts dedicated to CJC-1295 no DAC peptides.
You can buy CJC-1295 no DAC for Norway research which is available in a range of formulations including blends, stacks, nasal sprays and subcutaneous injections (e.g., peptide vials and pre-mixed pens). When considering to buy CJC-1295 no DAC, it is essential to source from reputable suppliers, such as Direct Sarms Norway, to guarantee the peptide’s quality and integrity, which is vital for securing reliable and consistent research results.
[1] M Alba, D Fintini, A Sagazio, et al (2006) Once-daily administration of CJC-1295, a long-acting growth hormone-releasing hormone (GHRH) analog, normalizes growth in the GHRH knockout mouse – American Journal of Physiology, Endocrinology and Metabolism, 2006 Dec, Volume 291 (Issue 6), Pages E1290-4.
[2] L Jetté, R Léger, K Thibaudeau, et al (2005) Human growth hormone-releasing factor (hGRF)1-29-albumin bioconjugates activate the GRF receptor on the anterior pituitary in rats: identification of CJC-1295 as a long-lasting GRF analog – Endocrinology, 2005 Jul, Volume 146 (Issue 7), Pages 3052-8.
[3] S L Teichman, A Neale, B Lawrence, et al (2005) Prolonged stimulation of growth hormone (GH) and insulin-like growth factor I secretion by CJC-1295, a long-acting analog of GH-releasing hormone, in healthy adults – The Journal of Clinical Endocrinology and Metabolism, 2006 Mar, Volume 91 (Issue 3), Pages 799-805.
[4] M Ionescu and L A Frohman (2006) Pulsatile secretion of growth hormone (GH) persists during continuous stimulation by CJC-1295, a long-acting GH-releasing hormone analog – Journal of Clinical Endocrinology and Metabolism, 2006 Dec, Volume 91 (Issue 12), Pages 4792-7.
[5] L Sackmann-Sala, J Ding, L A Frohman, and J J Kopchick (2009) Activation of the GH/IGF-1 axis by CJC-1295, a long-acting GHRH analog, results in serum protein profile changes in normal adult subjects – Growth Hormone & IGF Research,Volume 19, Issue 6, December 2009, Pages 471-477.
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